<!DOCTYPE html>
<html lang="en">
<head>
    <meta charset="UTF-8">
    <meta name="viewport" content="width=device-width, initial-scale=1.0">
    <meta http-equiv="X-UA-Compatible" content="ie=edge">
    <title>Document</title>
    <style>
        .box{
           display: flex;
            width: 300px;
            height: 300px;
            box-shadow: 0 0 5px rgba(0, 0, 0, .6);
            margin: 100px auto;
            justify-content: space-between;
            padding: 20px;
        }
        .item {
            width: 50px;
            height: 50px;
            border-radius: 50%;
            background: #000;
        }
        .item:nth-child(2) {
            align-self: center;
        }
        .item:nth-child(3) {
            align-self: flex-end;
        }
    </style>
</head>
<body>
    <div class="box">
        <div class="item"></div>
        <div class="item"></div>
        <div class="item"></div>
    </div>
</body>
</html>